Defensin beta 4 antibody (AA 3-39)

Catalog No. ABIN192001

The Mouse Monoclonal anti-Defensin beta 4 antibody (Clone L13-10-D1) (ABIN192001) specifically detects Defensin beta 4 in WB, RIA, EIA, IHC (fro) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Defensin beta 4 antibody (AA 3-39) (ABIN192001)

Target: Defensin beta 4 (DEFB4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Defensin beta 4 antibody is un-conjugated

Application: Western Blotting (WB), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: L13-10-D1

Product Details anti-Defensin beta 4 Antibody

Binding Specificity: AA 3-39

Specificity: This antibody detects Human beta-Defensin 4 (aa 3-39). There was cross reactivity obtained with Human beta-Defensin 1, beta-Defensin 2 and beta-Defensin 3.

Characteristics: Synonyms: DEFB104A, DEFB104B, DEFB4, Beta-defensin 4, BD-4, hBD-4, DEFB-4, DEFB104

Purification: Protein G Chromatography

Immunogen: Synthetic human β-Defensin 4 (aa 3-39)AA Sequence: ELDRICGYGTARCRKK(-)CRSQEYRIGRCPNTYACCLRK

Isotype: IgG1

Application Details

Application Notes: ELISA. RIA. Western blot. Immunohistochemistry (paraffin sections kidney 1 μg/mL). Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in aqua bidest to 1 mg/mL.

Buffer: 50 mM TRIS pH 7,4

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for Defensin beta 4

Target: Defensin beta 4 (DEFB4)

Alternative Name: Defensin beta 4

Background: Beta 4 Defensin has antimicrobial activity and synergistic effects with lysozyme and DEFB103. High expression levels are seen in the testis. Gastric antrum also exhibits relativey high levels. A lower exppression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression was observed in other tissues tested. Antimicrobial activity is decreased when the sodium chloride concentration is increased. Beta 4 Defensin belongs to the beta-defensin family.Synonyms: BD-4, Beta-defensin 4, DEFB-4, DEFB104, DEFB104A, DEFB104B, DEFB4, hBD-4

Gene ID: 140596

UniProt: Q8WTQ1