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CEACAM5 antibody

CEACAM5 Reactivity: Human FACS, IHC (p), IP, IHC (fro) Host: Mouse Monoclonal CB30 unconjugated
Catalog No. ABIN192374
  • Target See all CEACAM5 Antibodies
    CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
    Reactivity
    • 131
    • 21
    • 3
    • 3
    • 1
    Human
    Host
    • 93
    • 37
    • 1
    Mouse
    Clonality
    • 99
    • 32
    Monoclonal
    Conjugate
    • 68
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEACAM5 antibody is un-conjugated
    Application
    • 78
    • 75
    • 52
    • 49
    • 22
    • 20
    • 13
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    The mouse monoclonal antibody CB30 recognizes CD66e (CEA, 180-200 kDa), an extracellular cell surface-bound carcinoembryonic antigen mainly expressed on epithelial cells.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Human carcinoembryonic antigen (CEA, CEACAM5)
    Clone
    CB30
    Isotype
    IgG1
    Top Product
    Discover our top product CEACAM5 Primary Antibody
  • Application Notes
    Immunohistochemistry (paraffin sections): Staining technique: standard ABC technique (DAB+), recommended dilution: 10 μg/mL (1:100), positive tissue: adenocarcinoma of colon, pretreatment: 0,1 % pepsin in 0,1 M HCl for 30 min at room temperature.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
    Alternative Name
    CD66e (CEACAM5 Products)
    Synonyms
    CD66e antibody, CEA antibody, CEACAM5 antibody, CEACAM antibody, 1600029H12Rik antibody, Psg30 antibody, carcinoembryonic antigen related cell adhesion molecule 5 antibody, carcinoembryonic antigen antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, carcinoembryonic antigen-related cell adhesion molecule 8 antibody, carcinoembryonic antigen gene family antibody, CEACAM5 antibody, Ceacam5 antibody, LOC100409241 antibody, Cea antibody
    Background
    Carcinoembryonic antigen related cell adhesion mol,The CD66e (CEA, 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion. Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.,CEACAM5, CEA
    Gene ID
    1048
    UniProt
    P06731
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