PRKDC antibody (AA 2100-2150)

Catalog No. ABIN1926718

This Rabbit Polyclonal antibody specifically detects PRKDC in IHC, IF and IHC (p). It exhibits reactivity toward Human and Monkey.

Quick Overview for PRKDC antibody (AA 2100-2150) (ABIN1926718)

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKDC antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRKDC Antibody

Binding Specificity: AA 2100-2150

Specificity: Region between residue 2100 and 2150 of human DNA- Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:50 - 1:500), IHC, IHC-P (1:100 - 1:500)

Usage: Immunohistochemistry: Antigen retrieval is recommended. Antigen retrieval with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated. Human controls: Breast Carcinoma, Colon Carcinoma, Lung Adenocarcinoma, Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Testicular Seminoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline, 0.1 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for PRKDC

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Alternative Name: PRKDC / DNA-PKcs

Background: Name/Gene ID: PRKDC
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: PRKDC, DNA-PK, DNAPK, DNPK1, HYRC, HYRC1, p350, Scid, XRCC7, DNA-PK catalytic subunit, DNA-PKcs, p460, DNA-dependent protein kinase catalytic subunit

Gene ID: 5591

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response