PRKDC antibody (AA 4078-4128)

Catalog No. ABIN1926720

The Goat Polyclonal anti-PRKDC antibody (ABIN1926720) specifically detects PRKDC in WB, IHC, IF, IHC (p) and IP. The antibody is reactive with Human, Mouse, Rat, Cow, Guinea Pig and Pig samples.

Quick Overview for PRKDC antibody (AA 4078-4128) (ABIN1926720)

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This PRKDC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-PRKDC Antibody

Binding Specificity: AA 4078-4128

Specificity: Region between residue 4078 to 4128 of human Protein Kinase, DNA-Activated, Catalytic Polypeptide using the numbering given in entry NP_008835.5 (GeneID 5591).

Purification: Immunoaffinity purified

Application Details

Application Notes: Approved: IF (1:500 - 1:2500), IHC, IHC-P (1:1000 - 1:5000), IP (2 - 10 μg/mg lysate), WB (1:2000 - 1:10000)

Usage: Immunohistochemistry: Antigen retrieval with citrate buffer  pH 6.0 is recommended for FFPE tissue sections. Human controls: Breast Carcinoma, Colon Carcinoma, Non-Small Cell Lung Cancer, Ovarian Carcinoma, Prostate Carcinoma, Stomach Adenocarcinoma, Testicular Seminoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for PRKDC

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Alternative Name: PRKDC / DNA-PKcs

Background: Name/Gene ID: PRKDC
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: PRKDC, DNA-PK, DNAPK, DNPK1, HYRC, HYRC1, p350, Scid, XRCC7, DNA-PK catalytic subunit, DNA-PKcs, p460, DNA-dependent protein kinase catalytic subunit

Gene ID: 5591

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response