RAPGEF2 antibody (AA 975-1025)

Catalog No. ABIN1929244

This Rabbit Polyclonal antibody specifically detects RAPGEF2 in IHC (p), IF and IHC. It exhibits reactivity toward Human, Mouse, Dog, Horse, Rabbit, Guinea Pig and Pig.

Quick Overview for RAPGEF2 antibody (AA 975-1025) (ABIN1929244)

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Reactivity: Human, Mouse, Dog, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-RAPGEF2 Antibody

Binding Specificity: AA 975-1025

Specificity: Region between residue 975 and 1025 of human PDZ domain containing guanine nucleotide exchange factor (GEF) 1 using the numbering given in entry NP_055062.1 (GeneID 9693).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:50 - 1:500), IHC, IHC-P (1:100 - 1:500)

Usage: Immunohistochemistry: Antigen retrieval is recommended. Antigen retrieval with citrate buffer or Tris-EDTA  pH 9.0 buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated. Human controls: Anaplastic Thyroid Carcinoma, Breast Carcinoma, Colon Carcinoma, Lung Adenocarcinoma, Ovarian Carcinoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline, 0.1 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for RAPGEF2

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Alternative Name: RAPGEF2

Background: Name/Gene ID: RAPGEF2

Synonyms: RAPGEF2, CNrasGEF, DKFZP586O1422, NRap GEP, NRAPGEP, PDZ-GEF1, Rap-GEP, KIAA0313, PDZGEF1, RA(Ras/Rap1A-associating)-GEF, RA-GEF

Gene ID: 9693

Pathways: Neurotrophin Signaling Pathway