Topoisomerase II alpha antibody (C-Term)

Catalog No. ABIN1943283

This anti-Topoisomerase II alpha antibody is a Rabbit Polyclonal antibody detecting Topoisomerase II alpha in WB, IHC, IF, IHC (p) and IP. Suitable for Human.

Quick Overview for Topoisomerase II alpha antibody (C-Term) (ABIN1943283)

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Topoisomerase II alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-Topoisomerase II alpha Antibody

Binding Specificity: AA 1500-1531, C-Term

Specificity: Region between residue 1500 and the C-terminus (residue 1531) of human Topoisomerase (DNA) II Alpha using the numbering given in entry NP_001058.2 (GeneID 7153).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:250 - 1:1000), IHC, IHC-P (1:500 - 1:2000), IP (2 - 10 μg/mg lysate), WB (1:10000 - 1:30000)

Usage: Immunohistochemistry: Antigen retrieval with citrate buffer  pH 6.0 is recommended for FFPE tissue sections.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for Topoisomerase II alpha

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Alternative Name: TOP2A / Topoisomerase II Alpha

Background: Name/Gene ID: TOP2A
Family: Topoisomerase

Synonyms: TOP2A, DNA topoisomerase II, 170 kD, TOP2, DNA gyrase, DNA topoisomerase 2-alpha, TP2A

Gene ID: 7153

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases