Melatonin Receptor 1B antibody

Catalog No. ABIN1944815

The Rabbit Polyclonal anti-Melatonin Receptor 1B antibody has been validated for WB. It is suitable to detect Melatonin Receptor 1B in samples from Human. There are 2+ publications available.

Quick Overview for Melatonin Receptor 1B antibody (ABIN1944815)

Target: Melatonin Receptor 1B (MTNR1B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Melatonin Receptor 1B Antibody

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C,-20 °C

References for anti-Melatonin Receptor 1B antibody (ABIN1944815)

Ebisawa, Uchiyama, Kajimura, Kamei, Shibui, Kim, Kudo, Iwase, Sugishita, Jodoi, Ikeda, Ozeki, Watanabe, Sekimoto, Katoh, Yamada, Toyoshima, Okawa, Takahashi, Yamauchi: "Genetic polymorphisms of human melatonin 1b receptor gene in circadian rhythm sleep disorders and controls." in: Neuroscience letters, Vol. 280, Issue 1, pp. 29-32, (2000) (PubMed).

Reppert, Godson, Mahle, Weaver, Slaugenhaupt, Gusella: "Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 19, pp. 8734-8, (1995) (PubMed).

Target Details for Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Background: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Molecular Weight: 40188 Da

Gene ID: 4544

UniProt: P49286