Melatonin Receptor 1B antibody (AA 270-350)

Catalog No. ABIN7215734

The Rabbit Polyclonal anti-Melatonin Receptor 1B antibody (ABIN7215734) specifically detects Melatonin Receptor 1B in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for Melatonin Receptor 1B antibody (AA 270-350) (ABIN7215734)

Target: Melatonin Receptor 1B (MTNR1B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Melatonin Receptor 1B Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-MEL-1B-R Polyclonal Antibody

Specificity: MEL-1B-R Polyclonal Antibody detects endogenous levels of MEL-1B-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human MEL-1B-R at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Melatonin Receptor 1B

Target: Melatonin Receptor 1B (MTNR1B)

Alternative Name: MEL-1B-R

Background: MTNR1B, Melatonin receptor type 1B, Mel-1B-R, Mel1b receptorMTNR1B encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. Melatonin receptor type 1B is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.

Molecular Weight: 40kD

Gene ID: 4544

UniProt: P49286