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Prostacyclin Receptor antibody

The Rabbit Polyclonal anti-Prostacyclin Receptor antibody has been validated for WB and IF. It is suitable to detect Prostacyclin Receptor in samples from Human. There are 4+ publications available.
Catalog No. ABIN1944827

Quick Overview for Prostacyclin Receptor antibody (ABIN1944827)

Target

See all Prostacyclin Receptor (PTGIR) Antibodies
Prostacyclin Receptor (PTGIR)

Reactivity

  • 43
  • 12
  • 5
  • 2
  • 2
Human

Host

  • 45
  • 4
Rabbit

Clonality

  • 45
  • 4
Polyclonal

Conjugate

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Prostacyclin Receptor antibody is un-conjugated

Application

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  • 16
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  • 7
  • 3
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Western Blotting (WB), Immunofluorescence (IF)
  • Isotype

    IgG1
  • Application Notes

    IF: 1:100. WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    Storage

    4 °C,-20 °C
  • Ogawa, Tanaka, Inoue, Yoshitake, Isse, Nakagawa, Usui, Itoh, Yoshimasa, Narumiya: "Structural organization and chromosomal assignment of the human prostacyclin receptor gene." in: Genomics, Vol. 27, Issue 1, pp. 142-8, (1995) (PubMed).

    Boie, Rushmore, Darmon-Goodwin, Grygorczyk, Slipetz, Metters, Abramovitz: "Cloning and expression of a cDNA for the human prostanoid IP receptor." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 12173-8, (1994) (PubMed).

    Katsuyama, Sugimoto, Namba, Irie, Negishi, Narumiya, Ichikawa: "Cloning and expression of a cDNA for the human prostacyclin receptor." in: FEBS letters, Vol. 344, Issue 1, pp. 74-8, (1994) (PubMed).

    Nakagawa, Tanaka, Usui, Harada, Sasaki, Itoh, Yoshimasa, Namba, Narumiya, Nakao: "Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system." in: Circulation, Vol. 90, Issue 4, pp. 1643-7, (1994) (PubMed).

  • Target

    Prostacyclin Receptor (PTGIR)

    Alternative Name

    Prostacyclin Receptor

    Background

    Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.

    Molecular Weight

    40956 Da

    Gene ID

    5739

    UniProt

    P43119

    Pathways

    cAMP Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling
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