MAD2L1 antibody

Catalog No. ABIN1944831

This anti-MAD2L1 antibody is a Rabbit Polyclonal antibody detecting MAD2L1 in WB. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for MAD2L1 antibody (ABIN1944831)

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD2L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAD2L1 Antibody

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C,-20 °C

References for anti-MAD2L1 antibody (ABIN1944831)

Gemma, Hosoya, Seike, Uematsu, Kurimoto, Hibino, Yoshimura, Shibuya, Kudoh, Emi: "Genomic structure of the human MAD2 gene and mutation analysis in human lung and breast cancers." in: Lung cancer (Amsterdam, Netherlands), Vol. 32, Issue 3, pp. 289-95, (2001) (PubMed).

Target Details for MAD2L1

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Alternative Name: MAD2L1

Background: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore- spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Molecular Weight: 23510 Da

Gene ID: 4085

UniProt: Q13257