Hsc70 antibody (C-Term)

Catalog No. ABIN1944844

This Rabbit Polyclonal antibody specifically detects Hsc70 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for Hsc70 antibody (C-Term) (ABIN1944844)

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hsc70 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB16528

Product Details anti-Hsc70 Antibody

Binding Specificity: AA 539-569, C-Term

Predicted Reactivity: B, Ha, Hs, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HSPA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-569 amino acids from the C-terminal region of human HSPA8.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Hsc70 antibody (ABIN1944844)

Tsukahara, Yoshioka, Muraki: "Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70." in: Molecular pharmacology, Vol. 58, Issue 6, pp. 1257-63, (2000) (PubMed).

Egerton, Moritz, Druker, Kelso, Simpson: "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes." in: Biochemical and biophysical research communications, Vol. 224, Issue 3, pp. 666-74, (1996) (PubMed).

Target Details for Hsc70

Target: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Alternative Name: HSPA8

Background: HSPA8 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 is a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. The protein also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell.

Molecular Weight: 70898

Gene ID: 3312

NCBI Accession: NP_006588, NP_694881

UniProt: P11142