DUSP16 antibody

Catalog No. ABIN1944866

There are 4+ publications for this product available. The Rabbit Polyclonal anti-DUSP16 antibody is suitable to detect DUSP16 in samples from Human and Mouse. It has been validated for WB and IF.

Quick Overview for DUSP16 antibody (ABIN1944866)

Target: DUSP16 (Dual Specificity Phosphatase 16 (DUSP16))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP16 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-DUSP16 Antibody

Isotype: IgG

Application Details

Application Notes: IF: 1:100. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C,-20 °C

References for anti-DUSP16 antibody (ABIN1944866)

Willoughby, Collins: "Dynamic interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2." in: The Journal of biological chemistry, Vol. 280, Issue 27, pp. 25651-8, (2005) (PubMed).

Masuda, Shima, Katagiri, Kikuchi: "Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446." in: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 32448-56, (2003) (PubMed).

Hoornaert, Marynen, Goris, Sciot, Baens: "MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation." in: Oncogene, Vol. 22, Issue 49, pp. 7728-36, (2003) (PubMed).

Masuda, Shima, Watanabe, Kikuchi: "MKP-7, a novel mitogen-activated protein kinase phosphatase, functions as a shuttle protein." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 39002-11, (2001) (PubMed).

Target Details for DUSP16

Target: DUSP16 (Dual Specificity Phosphatase 16 (DUSP16))

Alternative Name: DUSP16

Background: Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.

Molecular Weight: 73102 Da

Gene ID: 80824

UniProt: Q9BY84