MCM2 antibody (pSer108)

Catalog No. ABIN1959485

The Rabbit Polyclonal anti-MCM2 antibody is suitable to detect MCM2 in samples from Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Chicken. It has been validated for IHC, IF and IHC (p).

Quick Overview for MCM2 antibody (pSer108) (ABIN1959485)

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MCM2 Antibody

Binding Specificity: pSer108

Specificity: Human MCM2 (phospho-Ser108)

Purification: Immunoaffinity purified

Immunogen: Phosphorylated synthetic peptide, which represented a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 108 according to the numbering given in entry NP_0045117.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:50 - 1:500), IHC, IHC-P (1:100 - 1:500)

Usage: Immunohistochemistry: Antigen retrieval is recommended. Antigen retrieval with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated. Human controls: Breast Carcinoma, Colon Carcinoma, Laryngeal Squamous Cell Carcinoma, Skin, Small Cell Lung Cancer, Testicular Seminoma. Mouse controls: Squamous Cell Carcinoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline, 0.1 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for MCM2

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Alternative Name: MCM2

Background: Name/Gene ID: MCM2

Synonyms: MCM2, BM28, Cell devision cycle-like 1, D3S3194, Cdc19, Cyclin-like 1, KIAA0030, Nuclear protein BM28, CDCL1, MITOTIN

Gene ID: 4171

NCBI Accession: NP_0045117

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA