ICAM-3/CD50 antibody
Quick Overview for ICAM-3/CD50 antibody (ABIN1967144)
Target
See all ICAM-3/CD50 (ICAM3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Monoclonal antibody MEM-04 reacts with CD50 (ICAM-3), a 120-130 kD type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells, it is negative on platelets and erythrocytes. The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).
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Purification
- Protein A purified
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Sterility
- Sterile filtered
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Immunogen
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Leukocytes of a patient suffering from LGL-type leukemia.
Type of Immunogen: Cells -
Isotype
- IgG1
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Application Notes
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Approved: Block, Flo, Func, IHC, IHC-P, Neut
Usage: Flow Cytometry: Recommended dilution - 5 μg/mL. Immunohistochemistry (paraffin sections): Recommended dilution - 10 μg/mL. Positive tissue - tonsil. Functional Application: The antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1). -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, sterile filtered.
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Handling Advice
- Do not freeze.
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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Alternative Name
- ICAM3 / CD50
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Background
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Name/Gene ID: ICAM3
Family: ICAM
Synonyms: ICAM3, CD50, CDW50, ICAM-R, CD50 antigen, ICAM-3 -
Gene ID
- 3385
Target
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