Stathmin 1 antibody (Ser24)

Catalog No. ABIN197454

This anti-Stathmin 1 antibody is a Rabbit Polyclonal antibody detecting Stathmin 1 in WB, IF and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for Stathmin 1 antibody (Ser24) (ABIN197454)

Target: Stathmin 1 (STMN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Stathmin 1 Antibody

Binding Specificity: Ser24

Specificity: Stathmin 1 antibody detects endogenous levels of total Stathmin 1 protein.

Purification: Affinity chromatography

Immunogen: Synthetic non-phosphopeptide derived from human Stathmin 1around the phosphorylation site of serine 24 (I-L-Sp-P-R).

Application Details

Application Notes: Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50approx. 1: 100 (suitable for paraffin-embedded sections).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin / STMN1

Background: This protein is a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19

Gene ID: 3925

NCBI Accession: NP_001138926

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics