Endothelin antibody (C-Term)

Catalog No. ABIN198264

Product Details anti-Endothelin Antibody

Target: Endothelin

Binding Specificity: C-Term

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This Endothelin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.

Purification: Protein G purified

Immunogen: Synthetic peptide corresponding to the c-terminal region of human endothelin (C, H, L, D, I, I, W), conjugated to BSA.

Type of Immunogen: Synthetic peptide

Clone: 3G10

Isotype: IgG2b

Application Details

Application Notes: Approved: IHC, IHC-Fr, RIA

Usage: Immunohistology: Frozen sections processed with dry acetone are recommended. Paraformaldehyde is not recommended as it destroys the epitope.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for Endothelin

Target: Endothelin

Abstract: Endothelin Products

UniProt: P05305