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Integrin beta 3 antibody

This Mouse Monoclonal antibody specifically detects Integrin beta 3 in FACS, IP and ICC. It exhibits reactivity toward Human.
Catalog No. ABIN198844

Quick Overview for Integrin beta 3 antibody (ABIN198844)

Target

See all Integrin beta 3 (ITGB3) Antibodies
Integrin beta 3 (ITGB3)

Reactivity

  • 248
  • 96
  • 62
  • 16
  • 15
  • 13
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  • 11
  • 8
  • 8
  • 5
  • 2
  • 2
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  • 1
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  • 1
  • 1
Human

Host

  • 157
  • 96
  • 11
  • 2
Mouse

Clonality

  • 142
  • 122
Monoclonal

Conjugate

  • 131
  • 17
  • 16
  • 10
  • 7
  • 6
  • 6
  • 6
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  • 5
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  • 2
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  • 2
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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This Integrin beta 3 antibody is un-conjugated

Application

  • 139
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  • 91
  • 52
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  • 36
  • 27
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  • 15
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  • 5
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  • 2
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  • 1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
  • Specificity

    Reacts with human integrin beta 3 (GPIIIa, vitronectin receptor beta chain).

    Purification

    Purified

    Immunogen

    Normal blood mononuclear cells activated by mixed lymphocyte reaction and cultured for 10 days in medium containing IL-2.

    Type of Immunogen: Cells

    Isotype

    IgM
  • Application Notes

    Approved: Flo, ICC, IP

    Usage: Immunoprecipitation. Immunocytochemistry (acetone fixation required). Flow cytometry. Inhibits platelet aggregation, 10 μg/mL. Storage and Handling: Maintain between 2 and 8?C, for 12 months. Protect from light. Do not store in diluted format.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Buffer of 0.01 M phosphate, 0.15 M sodium chloride,  pH 7.1, no preservatives, not guaranteed sterile.

    Preservative

    Without preservative

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    Integrin beta 3 (ITGB3)

    Alternative Name

    ITGB3 / Integrin Beta 3 / CD61

    Background

    Name/Gene ID: ITGB3
    Family: Integrin

    Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3

    Gene ID

    3690

    UniProt

    P05106

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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