Connexin 43/GJA1 antibody (C-Term)

Catalog No. ABIN199020

This anti-Connexin 43/GJA1 antibody is a Mouse Monoclonal antibody detecting Connexin 43/GJA1 in WB, ELISA, IF and IHC (p). Suitable for Human, Rat, Mouse and Dog.

Quick Overview for Connexin 43/GJA1 antibody (C-Term) (ABIN199020)

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivity: Human, Rat, Mouse, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Connexin 43/GJA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Connexin 43/GJA1 Antibody

Binding Specificity: C-Term

Specificity: Recognizes rat Connexin 43 only when the serine at residue 368 is unphosphorylated. Does recognize Connexin 43 if it is phosphorylated at sites other than Ser368. In some cell types, cross-reactivity with a ~70kD protein of unknown identity has been observed. This cross-reactivity is likely due to a shared epitope. Species cross-reactivity: Canine, human, mouse.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to a cytoplasmic sequence located near the C-terminus of rat Connexin 43.

Type of Immunogen: Synthetic peptide

Isotype: IgG1 kappa

Application Details

Application Notes: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunolocalization and Electron Microscopy. ELISA: 0.1-1 ug/ml. Western Blot: 1-3 ug/ml.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Connexin 43/GJA1

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Alternative Name: GJA1 / CX43 / Connexin 43

Background: Name/Gene ID: GJA1
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJA1, Connexin-43, DFNB38, Connexin 43, Gap junction alpha-1 protein, GJAL, HSS, Gap junction protein alpha 1, ODDD, ODD, AVSD3, CX43, HLHS1, ODOD, SDTY3

Gene ID: 2697

UniProt: P17302

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization