Hemagglutinin antibody (HRP)

Catalog No. ABIN1992745

This Rabbit Polyclonal antibody specifically detects Hemagglutinin in ELISA and WB. It exhibits reactivity toward Influenza A Virus H7N9.

Quick Overview for Hemagglutinin antibody (HRP) (ABIN1992745)

Target: Hemagglutinin (HA)

Reactivity: Influenza A Virus H7N9

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hemagglutinin antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB)

Product Details anti-Hemagglutinin Antibody (HRP)

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogen: Recombinant Hemagglutinin protein

Isotype: IgG

Application Details

Application Notes: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C/-80 °C

Storage Comment: Upon delivery aliquot and store at -20 °C or -80 °C.

Target Details for Hemagglutinin

Target: Hemagglutinin (HA)

Alternative Name: Hemagglutinin

Target Type: Influenza Protein

Background: Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Synonyms: HA

UniProt: R4NN21