The Rabbit Polyclonal anti-Hemagglutinin antibody has been validated for ELISA and WB. It is suitable to detect Hemagglutinin in samples from Influenza A Virus H7N9.
Catalog No. ABIN1992746
Quick Overview for Hemagglutinin antibody (FITC) (ABIN1992746)
This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze.
Storage
-20 °C/-80 °C
Storage Comment
Upon delivery aliquot and store at -20 °C or -80 °C.
Target
Hemagglutinin (HA)
Alternative Name
Hemagglutinin
Target Type
Influenza Protein
Background
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Synonyms: HA