CD51/CD61 antibody (Biotin)

Catalog No. ABIN199328

The Mouse Monoclonal anti-CD51/CD61 antibody has been validated for IP, IF and Func. It is suitable to detect CD51/CD61 in samples from Human, Chicken, Rabbit, Cow, Dog, Monkey and Pig.

Quick Overview for CD51/CD61 antibody (Biotin) (ABIN199328)

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Reactivity: Human, Chicken, Rabbit, Cow, Dog, Monkey, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD51/CD61 antibody is conjugated to Biotin

Application: Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func)

Product Details anti-CD51/CD61 Antibody (Biotin)

Specificity: Recognizes the human vitronectin receptor aVb3 complex, an RGD-directed adhesion receptor. Species cross-reactivity: bovine, chicken, monkey, porcine, canine, rabbit and avian. Not reactive with rat tissue.

Purification: Protein A purified

Immunogen: Purified adhesion receptor from the human melanoma cell line M21.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Func, IF, IP

Usage: Suitable for use in Immunoprecipitation, Immunofluorescence,. and Inhibition. Not suitable for immunohistochemical staining of paraffin-embedded tissue sections. Inhibition: Inhibits adhesion of cells to vitronectin coated surfaces at 10-25 μg/mL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.1, 0.1 % sodium azide, 15 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for CD51/CD61

Target: CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))

Alternative Name: Integrin Alpha V Beta 3