ORC4 antibody (AA 1-436) (FITC)

Catalog No. ABIN1993393

This Rabbit Polyclonal antibody specifically detects ORC4 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for ORC4 antibody (AA 1-436) (FITC) (ABIN1993393)

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC4 antibody is conjugated to FITC

Application: ELISA, Western Blotting (WB)

Product Details anti-ORC4 Antibody (FITC)

Binding Specificity: AA 1-436

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Origin recognition complex subunit 4 protein (1-436AA)

Isotype: IgG

Application Details

Application Notes: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ORC4

Target: ORC4 (Origin Recognition Complex, Subunit 4 (ORC4))

Alternative Name: ORC4

Background:

Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Aliases: cognition complex, subunit 4, S. cerevisiae, homolog of antibody, FLJ46668 antibody, HSORC4 antibody, ORC 4 antibody, ORC 4L antibody, ORC 4P antibody, ORC4 antibody, ORC4_HUMAN antibody, ORC4L antibody, ORC4L protein antibody, ORC4P antibody, Origin recognition complex subunit 4 (yeast homolog) like antibody, Origin recognition complex subunit 4 antibody, Origin recognition complex subunit 4 like (yeast) antibody, Origin recognition complex subunit 4 like antibody, origin recognition complex, subunit 4 homolog antibody, Origin recognition complex, subunit 4, S. cerevisiae, homolog-like antibody

UniProt: O43929

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA