LKB1 antibody (AA 1-433)

Catalog No. ABIN199386

This anti-LKB1 antibody is a Mouse Monoclonal antibody detecting LKB1 in WB and ICC. Suitable for Human, Mouse and Rat.

Quick Overview for LKB1 antibody (AA 1-433) (ABIN199386)

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This LKB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-LKB1 Antibody

Binding Specificity: AA 1-433

Specificity: Recognizes LKB1, Mr 51kD. An additional protein was also detected, Mr 90kD. Species cross-reactivity: Human, mouse and rat.

Purification: Protein G purified

Immunogen: GST fusion protein corresponding to residues 1-433 of human LKB1.

Type of Immunogen: Fusion protein

Isotype: IgG

Application Details

Application Notes: Approved: ICC (5 μg/mL), WB

Usage: Suitable for use in Western Blot and Immunocytochemistry. Proteins were visualized using a IgG (HRP) goat anti-mouse and a chemiluminescence detection system. Immunocytochemistry: 5 μg/mL detected LKB1 in transfected Cos-7 cells fixed with 3-7 % paraformaldehyde and permeabilized with 0.1 % Triton X-100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 70 % storage buffer (0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide), 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for LKB1

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Alternative Name: STK11 / LKB1

Background: Name/Gene ID: STK11
Subfamily: CAMKL
Family: Protein Kinase

Synonyms: STK11, HLKB1, Peutz-Jeghers syndrome, PJS, Serine/threonine kinase 11, Liver kinase B1, LKB1

Gene ID: 6794

UniProt: Q15831

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect