ADAM17 antibody (C-Term)

Catalog No. ABIN201454

This Rabbit Polyclonal antibody specifically detects ADAM17 in WB and ICC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ADAM17 antibody (C-Term) (ABIN201454)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM17 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-ADAM17 Antibody

Binding Specificity: C-Term

Specificity: 80 to 130 kDa bands can be detected, which may represent mature protein, precursor, and glycosylated TACE.

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: ICC, WB (1:500 - 1:2000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name: ADAM17 / TACE

Background: Name/Gene ID: ADAM17
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAM17, CD156B, CD156b antigen, CSVP, ADAM 17, NISBD, TNF-alpha converting enzyme, TNF-alpha convertase, TNF-alpha-converting enzyme, Snake venom-like protease, TACE

Gene ID: 6868

UniProt: P78536

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus