Reticulon 4 antibody (Internal Region)
Quick Overview for Reticulon 4 antibody (Internal Region) (ABIN204439)
Target
See all Reticulon 4 (RTN4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Specificity
- Specific for rat Nogo-A. On Western blots for rat brain homogenates, it identifies a band at ~190kD. The faint bands at lower molecular weights may represent the deglycosylated form (s) or degradation product (s) of rat Nogo-A. Reactivity has been confirmed with rat brain homogenates. Based on amino acid sequence homolog, cross-reactivity with human is expected.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic peptide derived from the internal region of rat Nogo-A (Reticulon 4-A, Foocen, Glut4 Vesicle 20kD Protein), which differs from the human sequence by only one amino acid.
Type of Immunogen: Synthetic peptide
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Application Notes
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Approved: IP, WB (0.5 - 2 μg/mL)
Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 0.5-2 μg/mL. Immunoprecipitation: 7 μg/Reaction. -
Comment
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Target Species of Antibody: Rat
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.1 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Reticulon 4 (RTN4)
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Alternative Name
- RTN4 / Nogo
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Background
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Name/Gene ID: RTN4
Family: Reticulon
Synonyms: RTN4, Human NogoA, My043 protein, Neurite outgrowth inhibitor, NOGOC, NSP-CL, Nogo protein, KIAA0886, Reticulon 5, Reticulon-4, Reticulon-5, Reticulon 4, RTN4-B1, RTN-X, RTN4-A, RTN4-B2, RTN4-C, Nbla00271, Neurite growth inhibitor 220, NI220/250, NOGO-A, Nogo-C, ASY, Foocen, Nbla10545, NOGO, Nogo-B, NSP -
Gene ID
- 57142
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UniProt
- Q9NQC3
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
Target
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