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Reticulon 4 antibody (Internal Region)

This Rabbit Polyclonal antibody specifically detects Reticulon 4 in WB and IP. It exhibits reactivity toward Rat.
Catalog No. ABIN204439

Quick Overview for Reticulon 4 antibody (Internal Region) (ABIN204439)

Target

See all Reticulon 4 (RTN4) Antibodies
Reticulon 4 (RTN4)

Reactivity

  • 81
  • 55
  • 37
  • 5
  • 4
  • 4
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  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
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Rat

Host

  • 75
  • 3
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  • 2
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  • 2
Rabbit

Clonality

  • 70
  • 17
Polyclonal

Conjugate

  • 41
  • 4
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  • 2
  • 2
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  • 2
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  • 1
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  • 1
This Reticulon 4 antibody is un-conjugated

Application

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  • 17
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  • 1
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Western Blotting (WB), Immunoprecipitation (IP)
  • Binding Specificity

    • 16
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    • 4
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    • 1
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    Internal Region

    Specificity

    Specific for rat Nogo-A. On Western blots for rat brain homogenates, it identifies a band at ~190kD. The faint bands at lower molecular weights may represent the deglycosylated form (s) or degradation product (s) of rat Nogo-A. Reactivity has been confirmed with rat brain homogenates. Based on amino acid sequence homolog, cross-reactivity with human is expected.

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic peptide derived from the internal region of rat Nogo-A (Reticulon 4-A, Foocen, Glut4 Vesicle 20kD Protein), which differs from the human sequence by only one amino acid.

    Type of Immunogen: Synthetic peptide
  • Application Notes

    Approved: IP, WB (0.5 - 2 μg/mL)

    Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 0.5-2 μg/mL. Immunoprecipitation: 7 μg/Reaction.

    Comment

    Target Species of Antibody: Rat

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.1 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target

    Reticulon 4 (RTN4)

    Alternative Name

    RTN4 / Nogo

    Background

    Name/Gene ID: RTN4
    Family: Reticulon

    Synonyms: RTN4, Human NogoA, My043 protein, Neurite outgrowth inhibitor, NOGOC, NSP-CL, Nogo protein, KIAA0886, Reticulon 5, Reticulon-4, Reticulon-5, Reticulon 4, RTN4-B1, RTN-X, RTN4-A, RTN4-B2, RTN4-C, Nbla00271, Neurite growth inhibitor 220, NI220/250, NOGO-A, Nogo-C, ASY, Foocen, Nbla10545, NOGO, Nogo-B, NSP

    Gene ID

    57142

    UniProt

    Q9NQC3

    Pathways

    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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