Transferrin Receptor antibody (FITC)

Catalog No. ABIN206052

This anti-Transferrin Receptor antibody is a Rat Monoclonal antibody detecting Transferrin Receptor in FACS, IHC, IP and IHC (fro). Suitable for Mouse.

Quick Overview for Transferrin Receptor antibody (FITC) (ABIN206052)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: YTA74-4

Product Details anti-Transferrin Receptor Antibody (FITC)

Specificity: Recognizes the mouse Transferrin receptor protein 1 also known as CD71 or TfR1. CD71 is a 763 amino acid glycoprotein homodimer of ~95 kD subunits. CD71 is expressed by dividing cells, and functions as a transferrin receptor mediating uptake of iron. Blocks the binding of R17 217.1.3. and R17 208.2 anti-TFR monoclonal antibodies.

Purification: Ion exchange chromatography

Immunogen: Concanavalin A activated mouse spleen cells.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:1), IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71 / Transferrin Receptor

Background: Name/Gene ID: TFRC
Subfamily: Metallopeptidase M28B
Family: Protease

Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1

Gene ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis