Macrophage Scavenger Receptor 1 antibody (FITC)
Quick Overview for Macrophage Scavenger Receptor 1 antibody (FITC) (ABIN206139)
Target
See all Macrophage Scavenger Receptor 1 (MSR1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Recognizes the murine scavenger receptor class A (SRA), type I and II, also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e. g. atherosclerotic lesions. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. Recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
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Purification
- Protein G purified
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Immunogen
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RAW264 cell line.
Type of Immunogen: Cells -
Isotype
- IgG2b
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Application Notes
- Approved: Flo (1:10 - 1:50)
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Comment
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide, 1 % BSA
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles. Sensitive to light.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light.
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- Macrophage Scavenger Receptor 1 (MSR1)
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Alternative Name
- MSR1 / CD204
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Background
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Name/Gene ID: MSR1
Synonyms: MSR1, CD204 antigen, SCARA1, PhSR1, SR-A, CD204, PhSR2, SRA, MSR2 -
Gene ID
- 4481
Target
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