LAIR1 antibody (FITC)
Quick Overview for LAIR1 antibody (FITC) (ABIN206632)
Target
See all LAIR1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes human leukocyte-associated Ig-like receptor-1 (LAIR-1), a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other hematopoietic cells including B cells, but is not expressed by non-hematopoietic, platelets or erythrocytes. Clone NKTA255 is reported to inhibit NK cell triggering via CD16 Molecules. XXX recommend the use of MCA2242XZ for this purpose.
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Purification
- Protein G purified
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Immunogen
- NK cells lines B12.100 and AM.25.
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Isotype
- IgG1
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Application Notes
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Approved: Flo (1:1), IP, WB
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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Alternative Name
- LAIR1 / CD305
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Background
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Name/Gene ID: LAIR1
Family: Immunoglobulin
Synonyms: LAIR1, CD305, CD305 antigen, HLAIR1, LAIR-1 -
Gene ID
- 3903
Target
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