CFP antibody

Catalog No. ABIN206668

This Mouse Monoclonal antibody specifically detects CFP in IHC, ELISA, IHC (fro) and Func. It exhibits reactivity toward Human.

Quick Overview for CFP antibody (ABIN206668)

Target: CFP (Complement Factor P (CFP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CFP antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 10-18

Product Details anti-CFP Antibody

Specificity: Recognizes human factor P, a 53 kD glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. Is reported to inhibit the function of factor P. Removal of Sodium Azide is recommended prior to use in functional assays. XXX recommend the use of EQU003 for this purpose.

Purification: Protein A purified

Immunogen: Native purified factor P from human serum.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Borate buffered saline,  pH 8.2, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CFP

Target: CFP (Complement Factor P (CFP))

Alternative Name: Properdin / CFP

Background: Name/Gene ID: CFP

Synonyms: CFP, Complement factor P, Complement factor properdin, PFC, PFD, Properidin, BFD, Properdin, Properdin P factor, complement

Gene ID: 5199

UniProt: P27918

Pathways: Complement System