CFP antibody (AA 197-223)
Quick Overview for CFP antibody (AA 197-223) (ABIN3030563)
Target
See all CFP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 197-223
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Purpose
- CFP Antibody / Complement Factor P / Properdin
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the CFP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the CFP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CFP (Complement Factor P (CFP))
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Alternative Name
- CFP
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Background
- This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
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UniProt
- P27918
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Pathways
- Complement System
Target
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