LYN antibody (AA 8-238)

Catalog No. ABIN207052

This Mouse Monoclonal antibody specifically detects LYN in WB, IP, ICC and Inhibition. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LYN antibody (AA 8-238) (ABIN207052)

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This LYN antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Blocking Antibody (Inhibition)

Clone: LYN-01

Product Details anti-LYN Antibody

Binding Specificity: AA 8-238

Specificity: Reacts with Lyn, a 58 kD cell signaling molecule (member of Src family) expressed in hematopoietic tissues.

Purification: Protein A purified

Immunogen: Bacterially expressed recombinant fragment of human Lyn (aa 8 - 238).

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ICC, Inhb, IP (1 - 2 μg/mL), WB (1 - 2 μg/mL)

Usage: Western Blotting: Recommended dilution -. 1-2 μg/mL, 60 min. Positive control -. RBL rat basophilic leukemia cell line. JURKAT human peripheral blood T cell leukemia cell line. A-431 human epidermoid carcinoma cell line. U-937 human histiocytic lymphoma c

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for LYN

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Alternative Name: LYN

Background: Name/Gene ID: LYN
Subfamily: Src
Family: Protein Kinase

Synonyms: LYN, Lyn protein tyrosine kinase, Lyn ptk, Lyn tyrosine kinase, p56Lyn, p53Lyn, Tyrosine-protein kinase Lyn, JTK8, Lyn kinase

Gene ID: 4067

UniProt: P07948

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling