beta-2 Microglobulin antibody (PE)
Quick Overview for beta-2 Microglobulin antibody (PE) (ABIN207236)
Target
See all beta-2 Microglobulin (B2M) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. beta2M is a 12 kD Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes.
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Purification
- Gel filtration
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Immunogen
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Purified human beta2-microglobulin.
Type of Immunogen: Purified protein -
Isotype
- IgG2a
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Application Notes
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Approved: Flo
Usage: The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, 0.2 % high-grade protease free BSA as a stabilizing agent.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze. Product is photosensitive and should be protected from light.
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Storage
- 4 °C
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Storage Comment
- Store at 4°C. Do not freeze. Protect from light.
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Alternative Name
- B2M / Beta 2 Microglobulin
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Background
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Name/Gene ID: B2M
Synonyms: B2M, Beta 2 Microglobulin, Beta-2-microglobulin, Beta-2-microglobin -
Gene ID
- 567
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UniProt
- P61769
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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