MLH1 antibody (AA 387-403)

Catalog No. ABIN208109

The Mouse Monoclonal anti-MLH1 antibody has been validated for WB. It is suitable to detect MLH1 in samples from Human, Monkey.

Quick Overview for MLH1 antibody (AA 387-403) (ABIN208109)

Target: MLH1 (MutL Homolog 1 (MLH1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This MLH1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 164C819

Product Details anti-MLH1 Antibody

Binding Specificity: AA 387-403

Specificity: In Molt-4, a 83 kD band is observed.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%) Gibbon (94%) Elephant, Panda, Bat, Dog, Rabbit (88%) Mouse, Hamster, Bovine, Horse, Pig, Opossum, Turkey, Chicken, Lizard, Xenopus (82%).

Purification: Protein G purified

Immunogen: This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 387-403 DSREQKLDAFLQPLSKP of human MLH1, GenBank no. NP_000240.1. This peptide sequence is 93% homologous to mouse and dog MLH1. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%), Gibbon (94%), Elephant, Panda, Bat, Dog, Rabbit (88%), Mouse, Hamster, Bovine, Horse, Pig, Opossum, Turkey, Chicken, Lizard, Xenopus (82%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (2 - 3 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for MLH1

Target: MLH1 (MutL Homolog 1 (MLH1))

Alternative Name: MLH1

Background: Name/Gene ID: MLH1

Synonyms: MLH1, COCA2, FCC2, HMLH1, HNPCC, HNPCC2, MutL protein homolog 1

Gene ID: 4292

NCBI Accession: NP_000240

UniProt: P40692

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response