ANTXR1 antibody (AA 481-497)

Catalog No. ABIN208216

Product Details anti-ANTXR1 Antibody

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Binding Specificity: AA 481-497

Reactivity: Human, Dog, Rabbit, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This ANTXR1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: TEM8 is observed at ~80 kD in western blots of HUVEC cells (Hotchkiss et al, 2005) and as an 80 kD and 85 kD double in human colon cell lysates (Nanada et al, 2004). The size difference is thought to be due to glycosylation as a 70 kD band was seen when cell extracts in Nanda et al (2004) were treated with a glycosidase cocktail. Nanda et al (2004) note a passage dependent loss of TEM8 in HUVEC suggesting that that TEM8 may be a specific marker of the endothelial cell (EC) phenotype which is lost as primary EC's age in culture and de-differentiate.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Panda, Rabbit (100%) Mouse, Rat, Bat, Elephant, Pig (94%) Horse, Opossum (88%).

Purification: Protein G purified

Immunogen: This monoclonal antibody was developed by immunizing mice with a synthetic peptide containing amino acids 481-497 (CINFTRVKNNQPAKYPL) of human TEM8. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Panda, Rabbit (100%), Mouse, Rat, Bat, Elephant, Pig (94%), Horse, Opossum (88%).

Type of Immunogen: Synthetic peptide

Clone: 200C1339(SB20)

Isotype: IgG1

Application Details

Application Notes: Approved: WB (1 - 3 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Short term: 4°C
Long term: -70°C.

Target Details for ANTXR1

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Alternative Name: ANTXR1 / TEM8 / ATR (ANTXR1 Products)

Synonyms: ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody

Background: Name/Gene ID: ANTXR1

Synonyms: ANTXR1, Tumor endothelial marker 8, Anthrax toxin receptor 1, TEM8

Gene ID: 84168

UniProt: Q9H6X2