MMP14 antibody (AA 160-173)

Catalog No. ABIN209031

This anti-MMP14 antibody is a Mouse Monoclonal antibody detecting MMP14 in WB, ELISA, IHC and IHC (p). Suitable for Human.

Quick Overview for MMP14 antibody (AA 160-173) (ABIN209031)

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MMP14 Antibody

Binding Specificity: AA 160-173

Specificity: Recognizes human MT1-MMP. Species cross-reactivity: Does not cross-react with mouse, rat or porcine.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Goat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%) Opossum, Platypus (93%).

Purification: Immunoaffinity purified

Immunogen: Peptide of aa160-173 [REVPYAYIREGHEK] in catalytic domain of human membrane-type 1 matrix metalloproteinase human MT1-MMP also referred to as MMP-14. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Goat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%), Opossum, Platypus (93%).

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P, WB (8 - 20 μg/mL)

Usage: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Western Blot: 8-20 μg/mL. Immunohistochemistry (Paraffin sections): 20 μg/mL. Requires periodate-lysine-paraformaldehyde for 18-24 hours at 4?C.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.0, 2 % BSA (protease free).

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for MMP14

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Alternative Name: MMP14 / MMP-14

Background: Name/Gene ID: MMP14
Subfamily: Metallopeptidase M10A
Family: Protease

Synonyms: MMP14, Membrane type-1 MMP, MT1-MMP, MT1MMP, MT-MMP, MT-MMP 1, Matrix metalloproteinase-14, MMP-14, MMP-X1, MTMMP1

Gene ID: 4323

UniProt: P50281

Pathways: Autophagy