Integrin beta 3 antibody

Catalog No. ABIN210819

This anti-Integrin beta 3 antibody is a Mouse Monoclonal antibody detecting Integrin beta 3 in WB, IHC and ICC. Suitable for Human.

Quick Overview for Integrin beta 3 antibody (ABIN210819)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-Integrin beta 3 Antibody

Specificity: Recognizes Integrin b3 (CD61), as determined by an independent laboratory. Mr ~115kD. Species cross-reactivity: Human.

Purification: Protein G purified

Immunogen: Human platelet membrane fraction.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ICC (5 - 20 μg/mL), IHC, WB

Usage: Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry. Immunocytochemistry: 5-20 μg/mL showed positive immunostaining for Integrin 3 (CD61) in HuVec cells fixed with 4 % paraformaldehyde followed by permeabilization with 0.25 % Triton X-100. Western Blot: Detects Integrin 3 (CD61) in WM852 and 1205Lu whole cell extracts. Immunohistochemistry: Detects Integrin 3 (CD61) in malignant melanoma sections.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: ITGB3 / Integrin Beta 3 / CD61

Background: Name/Gene ID: ITGB3
Family: Integrin

Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3

Gene ID: 3690

UniProt: P05106

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex