MUC1 antibody

Catalog No. ABIN210922

This Mouse Monoclonal antibody specifically detects MUC1 in IHC, WB, ELISA, FACS, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for MUC1 antibody (ABIN210922)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MUC1 Antibody

Specificity: Recognizes human CD227, the breast cancer associated mucin encoded by the Muc-1 gene. In normal tissues expression is restricted to specialized glandular epithelial. Recognizes the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin.

Purification: Protein G purified

Immunogen: Urinary MUC-1 mucin.

Isotype: IgG3

Application Details

Application Notes: Approved: ELISA (1:100 - 1:1000), Flo, IHC, IHC-Fr, IHC-P, WB

Usage: Suitable for use in Flow Cytometry, Immunohistochemistry, ELISA and Western Blot. Immunohistochemistry: Frozen, paraffin and resin sections. Does not require protein digestion pre-treatment of paraffin sections. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. ELISA: 1:100-1:1000. Positive control: Breast carcinoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: EMA / MUC1

Background: Name/Gene ID: MUC1
Family: Mucin

Synonyms: MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane

Gene ID: 4582

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling