SH3KBP1 antibody
Quick Overview for SH3KBP1 antibody (ABIN210960)
Target
See all SH3KBP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes the three SH3 domains of SETA, Mr ~85kD. SETA has multiple splice variants which can result in multiple bands when immunoblotting. Species cross-reactivity: Human, mouse and rat.
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Purification
- Protein G purified
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Immunogen
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6XHIS and HA tagged fusion protein corresponding to full length rat SETA.
Type of Immunogen: Fusion protein -
Isotype
- IgG2b kappa
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Application Notes
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Approved: IP, WB
Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot Analysis: 1-2 μg/mL of this lot detected SETA in RIPA lysates from NG108-15 cells. Immunoprecipitation: This antibody has been reported by an independent laboratory to immunoprecipitate SETA in human U87 glioma cells and rat primary astrocytes. -
Comment
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Target Species of Antibody: Rat
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 70 % storage buffer (0.1 M Tris glycine, pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide), 30 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))
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Alternative Name
- SH3KBP1 / CIN85
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Background
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Name/Gene ID: SH3KBP1
Synonyms: SH3KBP1, CD2BP3, CIN85, GIG10, HSB-1, HSB1, C-Cbl-interacting protein, CD2-binding protein 3, MIG18, Migration-inducing gene 18 -
Gene ID
- 30011
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UniProt
- Q96B97
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Pathways
- EGFR Signaling Pathway, EGFR Downregulation
Target
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