KIR2DL2 antibody (Extracellular Domain)

Catalog No. ABIN211120

This Mouse Monoclonal antibody specifically detects KIR2DL2 in FACS and IP. It exhibits reactivity toward Human.

Quick Overview for KIR2DL2 antibody (Extracellular Domain) (ABIN211120)

Target: KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIR2DL2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-KIR2DL2 Antibody

Binding Specificity: Extracellular Domain

Specificity: Recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

Purification: Purified

Immunogen: NK cell clone E57.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:10 - 1:50), IP

Usage: Suitable for use in Flow Cytometry and Immunoprecipitation. Flow Cytometry: 1:10-1:50. Use 10 μL to label 1 x10⁶ in 100 μL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.5 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for KIR2DL2

Target: KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))

Alternative Name: KIR2DL2 / CD158b

Background: Name/Gene ID: KIR2DL2
Family: Immunoglobulin

Synonyms: KIR2DL2, CD158B1, Cl-43, CD158k, MHC class I NK cell receptor, NKAT6, NKAT-6, p58 NK receptor CL-43, p58.2, CD158b, CD158b1 antigen

Gene ID: 3803

UniProt: P43627