Synaptophysin antibody

Catalog No. ABIN211569

This anti-Synaptophysin antibody is a Mouse Monoclonal antibody detecting Synaptophysin in WB, IHC, IHC (p) and ELISA. Suitable for Human, Rat, Pig and Hamster.

Quick Overview for Synaptophysin antibody (ABIN211569)

Target: Synaptophysin (SYP)

Reactivity: Human, Rat, Pig, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA

Product Details anti-Synaptophysin Antibody

Specificity: Recognizes human synaptophysin, also known as Major synaptic vesicle protein p38. Synaptophysin is a 313 amino acid synaptic vesicle associated protein of ~38kD containing a single domain. Synaptophysin expression is ubiquitous in synaptic vesicle membranes where it is the most abundant protein and is involved in the regulation of endocytosis Loss and atypical expression of synaptophysin is noted in conditions such as Huntingdon's disease and Alzheimer's disease. Mutations in the synaptophysin gene have been identified and lead to a condition, Mental retardation, X-linked 96. Has been used for the detection of synaptophysin by immunofluorescence, immunohistochemistry and western blotting on murine, marmoset, rat, lapine and human tissues.

Purification: Gel filtration

Immunogen: Crude human synaptic immunoprecipitate.

Type of Immunogen: Protein extract

Isotype: IgM

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (1:25), WB (1:500)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: SYP / Synaptophysin

Background: Name/Gene ID: SYP

Synonyms: SYP, MRX, Synaptophysin, MRXSYP

Gene ID: 6855

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity