CD40 Ligand antibody

Catalog No. ABIN211600

This Mouse Monoclonal antibody specifically detects CD40 Ligand in FACS. It exhibits reactivity toward Human.

Quick Overview for CD40 Ligand antibody (ABIN211600)

Target: CD40 Ligand (CD40LG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 Ligand antibody is un-conjugated

Application: Flow Cytometry (FACS)

Product Details anti-CD40 Ligand Antibody

Specificity: Recognizes the human CD40 ligand, also known as CD154, TNF-related activation protein (TRAP) or T-cell antigen Gp39. CD154 is a 261 amino acid ~32kD single pass, type-1 transmembrane glycoprotein. CD154 is expressed on activated T lymphocytes, predominantly CD4 +ve and also on some basophils and mast cells. Binds to CD154 at an epitope distinct from the CD40 binding site.

Purification: Protein A purified

Immunogen: Mouse myeloma cell line transfected with human CD40L (CD154).

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:10 - 1:50)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD40 Ligand

Target: CD40 Ligand (CD40LG)

Alternative Name: CD40L

Background: Name/Gene ID: CD40LG
Family: TNF

Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein

Gene ID: 959

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints