MCAM antibody
Quick Overview for MCAM antibody (ABIN7470747)
Target
See all MCAM AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes the 118kD cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells. CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumor progression.
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Purification
- Protein G purified
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Immunogen
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Recombinant human MUC18 (D1-D5) Fc protein.
Type of Immunogen: Recombinant protein -
Isotype
- IgG1
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Application Notes
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Approved: ELISA, Flo (1:10 - 1:50), IHC, IHC-Fr
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Alternative Name
- MCAM / CD146
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Background
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Name/Gene ID: MCAM
Family: Immunoglobulin
Synonyms: MCAM, CD146, CD146 antigen, Gicerin, Melanoma adhesion molecule, MUC18, p1h12 -
Gene ID
- 4162
Target
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