MCL-1 antibody (AA 121-139)

Catalog No. ABIN212683

This Rabbit Polyclonal antibody specifically detects MCL-1 in WB. It exhibits reactivity toward Human, Dog, Pig, Monkey, Rabbit and Guinea Pig.

Quick Overview for MCL-1 antibody (AA 121-139) (ABIN212683)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human, Dog, Pig, Monkey, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCL-1 Antibody

Binding Specificity: AA 121-139

Specificity: This immunoaffinity purified antibody Detects a ~42/43kD protein doublet, corresponding to the expected molecular mass of Mcl-1 on SDS-PAGE immunoblots, in samples from human, canine, guinea pig, monkey, porcine and rabbit. The antibody specificity is confirmed by peptide inhibition studies. An additional protein at ~33kD may also be detected. Other additional proteins may also be seen in some samples.

Purification: Immunoaffinity purified

Immunogen: Human Mcl-1 synthetic peptide (amino acid residues 121-139), conjugated to KLH.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB

Usage: Western Blot (ECL): 0.1 μg/mL. Positive control: HeLa Heat Shocked Cell Lysate.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Borate buffered saline,  pH 8.2 25 mM sodium borate, 100 mM boric acid, 75 mM NaC1, 5 mM EDTA (disodium salt).

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1 / MCL 1

Background: Name/Gene ID: MCL1

Synonyms: MCL1, BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, MCL1S, MCL1L, Myeloid cell leukemia ES, MCL 1, MCL1-ES, TM, EAT, Mcl-1

Gene ID: 4170

UniProt: Q07820

Pathways: MAPK Signaling