PDE2A antibody (N-Term)

Catalog No. ABIN213546

This anti-PDE2A antibody is a Rabbit Polyclonal antibody detecting PDE2A in IHC and IHC (p). Suitable for Human, Dog and Horse.

Quick Overview for PDE2A antibody (N-Term) (ABIN213546)

Target: PDE2A (phosphodiesterase 2A, CGMP-Stimulated (PDE2A))

Reactivity: Human, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE2A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDE2A Antibody

Binding Specificity: N-Term

Brand: IHC-plus™

Specificity: Human PDE2A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except KCNH2 (59 % ).

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla, Marmoset, Dog, Panda, Horse (100%) Gibbon, Monkey, Mouse, Rat, Bovine, Elephant, Rabbit (94%) Pig (88%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 17 amino acid peptide from N-terminus of human PDE2A. Percent identity with other species by BLAST analysis: Human, Gorilla, Marmoset, Dog, Panda, Horse (100%), Gibbon, Monkey, Mouse, Rat, Bovine, Elephant, Rabbit (94%), Pig (88%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDE2A

Target: PDE2A (phosphodiesterase 2A, CGMP-Stimulated (PDE2A))

Alternative Name: Pde2 / PDE2A

Background: Name/Gene ID: PDE2A
Subfamily: PDE - cAMP/cGMP dual-specific, cGMP-stimulated
Family: Phosphodiesterase

Synonyms: PDE2A, CGMP-stimulated PDE, Cyclic GMP-stimulated PDE, PDE2, Pde2a2, PED2A4, Phosphodiesterase 2A, CGS-PDE, CGSPDE, PDE2A1, Pde2a3

Gene ID: 5138

Pathways: cAMP Metabolic Process, Synaptic Membrane