FLT1 antibody (N-Term)

Catalog No. ABIN213617

The Rabbit Polyclonal anti-FLT1 antibody is suitable to detect FLT1 in samples from Human. It has been validated for IHC and IHC (p).

Quick Overview for FLT1 antibody (N-Term) (ABIN213617)

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FLT1 Antibody

Binding Specificity: N-Term

Specificity: Human VEGFR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset, Dog, Panda, Horse, Opossum (93%) Mouse, Rat, Platypus (87%) Bovine, Elephant, Rabbit (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 15 amino acid peptide from N-terminus of human VEGFR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey, Marmoset, Dog, Panda, Horse, Opossum (93%), Mouse, Rat, Platypus (87%), Bovine, Elephant, Rabbit (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 - 10 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5-10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FLT1

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Alternative Name: FLT1 / VEGFR1

Background: Name/Gene ID: FLT1
Subfamily: VEGF Receptor
Family: Protein Kinase

Synonyms: FLT1, FLT, FLT-1, Fms-related tyrosine kinase 1, SFlt1, VEGF-r1, VEG-R1, Tyrosine-protein kinase FRT, VEGFR-1, Fms-like tyrosine kinase 1, FRT, VEGF receptor 1, VEGFf-rI, VEGFR1

Gene ID: 2321

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals