CCL2 antibody

Catalog No. ABIN289500

Cited in 1 publication. The Rabbit Polyclonal anti-CCL2 antibody (ABIN289500) specifically detects CCL2 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CCL2 antibody (ABIN289500)

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCL2 Antibody

Purification: Purified

Immunogen: MCP1 antibody was raised in rabbit using highly pure recombinant human MCP-1(MCAF) as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 0.5-2 μg/mL, WB: 0.1-0.2 μg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of > 0.2 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from 0.5 x PBS, pH 7.4.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

References for anti-CCL2 antibody (ABIN289500)

Frøyland, Pedersen, Kvissel, Almaas, Pharo, Skålhegg, Mollnes, Rootwelt: "Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons." in: Brain research, Vol. 1113, Issue 1, pp. 64-73, (2006) (PubMed).

Target Details for CCL2

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: MCP1

Background: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species.

Molecular Weight: 8.6 kDa (predicted detection band MW)

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection