C3 antibody

Catalog No. ABIN214960

This Mouse Monoclonal antibody specifically detects C3 in WB, IHC and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for C3 antibody (ABIN214960)

Target: C3 (Complement Component 3 (C3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: H11

Product Details anti-C3 Antibody

Specificity: Recognizes human C3b, part of the complement system. C3 is cleaved by C3-convertase creating C3a and C3b, which binds to the surface of pathogens leading to their destruction by phagocytic cells. Recognizes a determinant present on native (circulating) C3 and on the fragments C3b and C3c. The antibody is directed to a determinant present on the beta chain of the C3 Molecule (Western blot). It does not react with the anaphylatoxin C3a or the fragment C3d and does not inhibit the hemolytic function of C3.

Purification: Protein A purified

Immunogen: Native human C3 / Complement C3.

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:10), WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS, 0.09 % sodium azide, 0.5 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.

Target Details for C3

Target: C3 (Complement Component 3 (C3))

Alternative Name: Complement C3 / C3b

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling