GJD2 antibody (Cytoplasmic Domain)

Catalog No. ABIN215719

This Rabbit Polyclonal antibody specifically detects GJD2 in WB and ELISA. It exhibits reactivity toward Rat and Mouse.

Quick Overview for GJD2 antibody (Cytoplasmic Domain) (ABIN215719)

Target: GJD2 (Gap Junction Protein, delta 2, 36kDa (GJD2))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GJD2 Antibody

Binding Specificity: Cytoplasmic Domain

Specificity: This antibody can be used to specifically detect the Cx36 protein (~36kD). Antibody specificity was confirmed by Western blotting with lysates from rat retina and olfactory bulb. A homodimer may be observed. Reacts with rat and mouse Cx36. Reactivity was confirmed by immunocytochemistry with frozen sections from rat brain (stained: olfactory bulb and inferior olive), retina (stained: inner and outer plexiform layers, inner nuclear layer) and spinal cord (stained: gray matter). Human reactivity is likely but has not been confirmed. Reactivity with other species has not been evaluated. Sample ELISA Western Blot Human Likely Mouse + Rat + Immunogen +.

Purification: Immunoaffinity purified

Immunogen: Peptide corresponding to a sequence located in the cytoplasmic loop between the second and third transmembrane domains of rat and mouse Connexin 36 (Cx36). This sequence differs from the human Cx36 protein by a single amino acid.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.1 - 1 μg/mL), WB (1 μg/mL)

Usage: Suitable for use in ELISA, Western Blot. ELISA: 0.1-1.0 μg/mL. Western Blot: 1 μg/mL.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for GJD2

Target: GJD2 (Gap Junction Protein, delta 2, 36kDa (GJD2))

Alternative Name: GJD2 / CX36 / Connexin 36

Background: Name/Gene ID: GJD2
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJD2, Connexin 36, Gap junction alpha-9 protein, Gap junction delta-2 protein, Gap junction protein alpha-9, Connexin-36, CX36

Gene ID: 57369

UniProt: Q9UKL4