alpha 2 Antiplasmin antibody (AA 161-260) (AbBy Fluor® 488)

Catalog No. ABIN2170079

The Rabbit Polyclonal anti-alpha 2 Antiplasmin antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect alpha 2 Antiplasmin in samples from Human, Mouse and Rat.

Quick Overview for alpha 2 Antiplasmin antibody (AA 161-260) (AbBy Fluor® 488) (ABIN2170079)

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 2 Antiplasmin antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-alpha 2 Antiplasmin Antibody (AbBy Fluor® 488)

Binding Specificity: AA 161-260

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SERPINF2/Alpha 2 antiplasmin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Alternative Name: Alpha 2 antiplasmin

Background:

Synonyms: A2AP, A2AP_HUMAN, AAP, Alpha 2 antiplasmin, Alpha 2 antiplasmin pigment epithelium derived factor, Alpha 2 AP, ALPHA 2 PI, Alpha 2 plasmin inhibitor, Alpha 2 plasmin inhibitor deficiency, Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-PI, Alpha-2-plasmin inhibitor, Antiplasmin deficiency, API, Plasmin inhibitor deficiency, PLI, Serine or cysteine peptidase inhibitor, clade F, member 2, Serine Or cysteine peptidase inhibitor, clade F, member 2, isoform CRA_c, Serine or cysteine proteinase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2, Serine Or cysteine proteinase inhibitor, clade F, member 2, Serine or cysteine peptidase inhibitor clade F member 2, Serpin F2, Serpin peptidase inhibitor clade F, Serpin peptidase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2, SERPINF2.

Background: Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID: 5345

UniProt: P08697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones