Casein alpha-S2 (CSN1S2) (AA 165-203) antibody

Catalog No. ABIN2170103

The Rabbit Polyclonal anti- antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect in samples from Cow and Mouse. There are 2+ publications available.

Quick Overview for Casein alpha-S2 (CSN1S2) (AA 165-203) antibody (ABIN2170103)

Target: Casein alpha-S2 (CSN1S2)

Reactivity: Cow, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 165-203

Cross-Reactivity: Cow, Mouse

Predicted Reactivity: Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from cow Alpha s2 Casein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References

Luo, Zhao, Zhang, Gao, Wang, Hanigan, Zheng: "SESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells." in: Scientific reports, Vol. 8, Issue 1, pp. 3912, (2019) (PubMed).

Gao, Hu, Zheng, Wang: "Leucine and histidine independently regulate milk protein synthesis in bovine mammary epithelial cells via mTOR signaling pathway." in: Journal of Zhejiang University. Science. B, Vol. 16, Issue 6, pp. 560-72, (2015) (PubMed).

Target Details

Target: Casein alpha-S2 (CSN1S2)

Alternative Name: Alpha s2 Casein

Background:

Synonyms: Alpha-S2-casein, CSN1S2

Background: Important role in the capacity of milk to transport calcium phosphate. Casocidin-I inhibits the growth of E.coli and S.carnosus.

Gene ID: 282209

UniProt: P02663